Gregg Araki’s breakthrough film begins with one of the most flippant HIV diagnoses in cinema when semi-employed film critic Jon (Gilmore) receives the news that so many dreaded. Meanwhile, hunky, reckless drifter Luke—who is also HIV positive—cruises into town in his newly acquired car (stolen from a pair of weirdos who pick him up hitchhiking). When the two cross paths, a combustible relationship is formed, and they ditch their lives to go on the road with the motto “f*ck everything.”